Ans.
A spicy ingredient of many curries may be an effective
treatment for Alzheimer's disease, say researchers. A
team from the University of California at Los Angeles
believes that turmeric may play a role in slowing down
the progression of the neurodegenerative disease.
The finding may help to explain why rates of Alzheimer's
are much lower among the elderly in India than in their
Western peers.
Previous studies have found that Alzheimer's affects just
1% of people over the age of 65 living in some Indian
villages.
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Vindaloos-
Turmeric is found in everything from mild Kormas to the
hottest Vindaloos. The crucial chemical is curcumin, a
compound found in the spice. Alzheimer's is linked to
the build up of knots in the brain called amyloid plaques.
Turmeric reduced the number of these plaques by a half.The
researchers also found that turmeric had other health
benefits. It aids digestion, helps fight infection and
guards against heart attacks. In the study, middle aged
and aged rats were fed a diet rich in curcumin.
All the rats received brain injections of amyloid to mimic
progressive Alzheimer's disease.Not only was there less
evidence of plaque build up in the curcumin-fed rats,
they also outperformed rats on normal diets when carrying
out maze-based memory tests.
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Curcumin also appeared to reduce Alzheimer's-related inflammation
in the brain tissue. Researcher Dr Sally Frautschy said
the compound had potential as a treatment for the prevention
of Alzheimer's disease - particularly in tandem with anti-inflammatory
drugs such as ibuprofen.
Dr Richard Harvey, director of research at the Alzheimer's
Society, said: "Curcumin has both anti-oxidant and
anti-inflammatory properties. "Drugs with similar
properties could potentially be used as preventative treatments
for Alzheimer's disease."
However, Dr Harvey warned that it could be many years
before such drugs were made widely available.
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